Biomolecular Aspect Of Physical Activity And Healthy Diet On Atherosclerosis Patomechanism In Cardiovascular Disease

  • Made Kurnia Widiastuti Giri
  • Bambang Purwanto
  • Herka Maya Jatmika

Abstract

The present article reviews the relationship between imbalance between physical activity and
dietary energy intake, how they affect the risk of cardiovascular diseases through biomolecular
analysis. Nowadays, sedentary lifestyle and overweight are major public health, clinical, and
economical problems in worldwide societies. The worldwide epidemic of excess weight is due to
imbalance between physical activity and dietary intake. Sedentary lifestyle, unhealthy diet, and
consequent overweight and obesity markedly increase the risk of cardiovascular diseases. Daily
physical activity shows substantial inter-individual variation, and low physical activity is associated
with obesity leads to increase cardiovascular incidence. An anamnesis, physical examination,
Electrocardiography, echocardiography and an adjuvant measure test on plasma of blood are
important to examine the atherosclerosis in cardiovascular system. Plasma test nowadays goes
to biomolecular aspect measures many proteins on plasma according to the process flows as
same as symptoms appear or its silent. Biomolecular test proteins such as citokines and
chemokines which are an important in inflammation chain process. Inflammation signed by an
unequal state of oxidant and antioxidant in the organ system. Healthy diet contains many
antioxidant and physical activity could decreased proinflammantory citokines so it would be the
best combination cutting the ile of biomolecular processed in atherosclerosis which is based on
inflammation. Thus, it is argued that the best way to lower the risk of cardiovascular diseases is
by implication of regular moderate intensity physical activity, a healthy diet, and avoiding
unhealthy weight gain are effective and safe ways to prevent and manage cardiovascular
diseases.

How to Cite
WIDIASTUTI GIRI, Made Kurnia; PURWANTO, Bambang; MAYA JATMIKA, Herka. Biomolecular Aspect Of Physical Activity And Healthy Diet On Atherosclerosis Patomechanism In Cardiovascular Disease. Proceeding ICIRAD, [S.l.], v. 1, n. 1, nov. 2015. Available at: <https://eproceeding.undiksha.ac.id/index.php/icirad/article/view/132>. Date accessed: 21 oct. 2020.